Progressive decline in muscle quality in people with inclusion body myositis is linked to poorer physical performance

Takeaway

  • Quantitative magnetic resonance imaging outcome measures correlate with physical performance measures in sporadic inclusion body myositis.

Why this matters?

  • Quantitative magnetic resonance imaging measures have been proposed as a non-invasive assessment tool to study sporadic inclusion body myositis muscle pathological processes.

  • In this unique study, several quantitative imaging parameters, such as muscular fat deposition, thigh muscle volume and muscle macromolecular structure, were valid and responsive measures which could further our knowledge of disease pathological processes and development of experimental drugs.